Particle Characterization

 

Credit Card payment method will no longer be accepted after AUGUST 30, 2015

                     

IST Provides a Wide Range of Particle Characterization Services — Size,  Distribution, Concentration, Surface Area, and more

LS Series Particle Analyzer

Standard 3-5 day turnaround on sample testing! 

One and two business day services are also available.

ImmunoSite Technologies, LLC (IST) specializes in the characterization of a diversity of materials ranging from dry powders and liquids to biological samples.  The IST team is highly skilled in analyzing particle size distribution (PSD), concentration, surface area, and more.

IST sample analysis expertise includes therapeutic drugs, biologics, pigments, filler compounds, toners, foods, abrasives, clay, minerals, construction materials, coating materials, metals, and many other sample types.  The team works with you to plan and conduct the type of analysis you need, with the added benefit of their expertise to develop assay methodologies to meet your most demanding samples.

Experienced Team, Beckman Coulter Trained, Quick Turnaround

You can count on professional and knowledgeable service from IST.  With 21 CFR part 11 analytical systems at your service, all samples are analyzed with superior methodologies.  All data undergoes extensive reviews, ensuring that you receive the best results possible.

Many of the seasoned IST particle characterization pros were formerly Beckman Coulter, Inc. (BEC) chemists, scientists, and engineers.  IST offers quick sample-analysis turnaround and superior customer service including strict confidentiality of all data and samples.  All protocols for sample handling and data reporting meet Good Laboratory Practices (GLP) standards.

Overview of the Instruments and Technologies Used at IST’s Testing Facility

PC Lab Scientists

Instrument Performance Qualification / Validation

If you are interested in purchasing a particle characterization instrument, IST provides instrument performance qualification and validations services to ensure and document that the instrument will perform as needed for your specific applications.

A.  Sample Submission Forms:

Shipping Address:     2831 Corporate Way, Miramar, FL 33025, USA

Service Request Form :  To provide details of the service that you wish, please copy and paste the link below into your web browser’s address bar, complete the form and return to us at particle@ist.us.com or call us at 954-462-6800.

     http://immunositetechnologies.com/wp-content/uploads/2017/06/POL-PC-1.01_Rev_AG_SRF_(editable_fields).pdf

Sample Content Form  To provide handling and safety instructions (if SDS is not available) please copy and paste the link below into your web browser’s address bar, complete the form and return to us at particle@ist.us.com or call us at 954-462-6800.

     http://immunositetechnologies.com/wp-content/uploads/2017/06/POL-PC-1.03_Rev_AG_Shipping_Instructions.pdf

Sample Shipping Instructions & Confidentiality  To determine proper shipping methods and sample quantity requirements,  please copy and paste the link below into your web browser’s address bar. If you have any questions or concerns, contact us at  particle@ist.us.com or call 954-462-6800. 

       http://immunositetechnologies.com/wp-content/uploads/2017/06/POL-PC-1.04_Rev_AG_Sample_Content_&_Safety_(editable_fields).pdf

Closer Look at the Services

Particle size analysis and particle counting (concentration):

The analysis of particulate samples is performed to define the particle size and distribution from a representative sample. Particle counting (number of particles with some physical characteristics in a unit volume of liquid or air) is reported as the result of either the total number of particles within the chosen lower and upper size boundaries or a particle size distribution with absolute count at each size bin.

Method Development and Validation:

IST provides a comprehensive quality assurance system  which is an essential component for analytical laboratories.  The validation services include performing tests designed to demonstrate that an analytical test system is suitable for its intended purpose and is capable of providing accurate and reproducible analytical data.  Method validation is required for 1) introduction of new methods to routine use, 2) implementation of changes to an existing method (e.g., an instrument with different characteristics or samples with a different matrix), and/or 3) changes to original intended use or scope of an existing method.

Performance Qualification (PQ):

Verifies compliance with all performance requirements specified in the User Requirements Specification (URS) and Standard Operating Procedures (SOPs).  The PQ includes tests designed to verify the satisfactory performance of the equipment or system that commences after the Installation Qualification (IQ) and Operational Qualification (OQ) have been completed successfully.

Technologies

Laser diffraction:

The laser diffraction particle size analyzer utilizes the Fraunhofer and Mie theories of light scattering.  For particles larger than 100 µm in diameter, the Fraunhofer model will produce results almost identical to those obtained with an optical model generated for the material and fluid. The Mie theory describes the interaction of light with a particle of arbitrary size as a function of angle, given that the wavelength and polarization of the light are known and that the particle is smooth, spherical, homogeneous, and of known refractive index for both the particles and the suspension fluid.

Coulter Principle

The Coulter Principle: the reference method for particle sizing.

The reference technology for counting and sizing particles using impedance measurements. Particles suspended in a weak electrolyte solution are drawn through a small aperture, the “sensing zone”, through which an electric current flows.  As each particle passes through the sensing zone, it displaces its own volume of conducting liquid and increases the electrical impedance in proportion to its size.  An amplifier converts the current fluctuation into a voltage pulse large enough to measure accurately.  According to the Coulter Principle, the amplitude of this pulse is proportional to the size of the particle traversing the orifice. Particles as small as 0.4 µm and as large as 1200 µm in diameter can routinely be measured.

Particle Testing Case Studies

Check here for a series of informative case studies on how different companies are using particle testing and characterization to achieve superior product performance and competitiveness.

Put IST to Your Test … Today

See what IST customers are saying now, and then see for yourself why laboratories and companies from all over the world rely on IST for particle characterization and particle testing services.  How can we help you?  We are happy to consult with you about the best approach to addressing your needs for quality control, process or production QC, and more.

Contact IST today and let us demonstrate our capabilities.

>>>Analytical Instrumentation utilized at the IST Particle Testing Facility

Phone toll free at 888-770-4478   or    954-462-6800

Email at particle@ist.us.com

For more details on particle characterization services, instruments and more, download the service brochure

Beckman Coulter and Coulter Counter are registered trademarks of Beckman Coulter, Inc.
LS and Multisizer are trademarks of Beckman Coulter, Inc.